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SmartMe&You-TELEMAIA

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4 December 2025

Legal and ethics advisors

are accomplished figures from the fields of ethics, privacy and data protection law, and ICT technology.

Publication

Abnormal Resting-State EEG delta and alpha rhythms in Huntington's and Alzheimer's Diseases: An exploratory study.

eBRAIN-Health calendar

meet the team - eBRAIN-Health represented on events

08 December 2025

EBRAINS Summit 2025

Medical data for enabling progress in healthcare in Europe and beyond

learn more EBRAINS Summit 2025

2 December 2025

European Parliament Lunch Debate

The topic of the lunch debate is “Future of dementia research in Europe”

European Parliament

29 November 2025

Cyberspace Conference

Synthetic Data in the European Data Strategy

learn more Cyberspace Conference

25 November 2025

Adopt AI International Summit

International Summit, 25-26 November, 2025, Grand Palais, Paris.

Adopt AI

The eBRAIN-Health achievements

Progress, news, publications, and press

2026

events and conference contributions

scientific publications

Jakhar D, Noce G, Del Percio C, Lopez S, Carducci F, Lizio R, De Bartolo M, Henao Isaza V, Macrì A, Soricelli A, Salvatore M, Ciccarelli G, Galluccio S, Di Cecca A, Aiello M, Güntekin B, Yener G, Massa F, Arnaldi D, Famà F, Pardini M, Ferri R, Lanuzza B, Stocchi F, Vacca L, Coletti C, Marizzoni M, Taylor JP, Hanoğlu L, Yırıkoğulları H, Kıyı Atilla İ, Kula H, Frisoni GB, Cuoco S, Barone P, Bonanni L, D'Anselmo A, Biundo R, Cauzzo S, Fiorenzato E, Antonini A, D'Antonio F, Bruno G, Fabbrini G, Conte A, Leodori G, Giubilei F, Infarinato F, Marziali S, De Pandis MF, Delussi M, Salvatore E, De Tommaso M, Babiloni C.
Abnormal Resting-State EEG delta and alpha rhythms in Huntington's and Alzheimer's Diseases: An exploratory study. Clin Neurophysiol. 2026 Jan 25;184:2111518. doi: 10.1016/j.clinph.2026.2111518. Epub ahead of print. PMID: 41619714.

Carpi M, Henao Isaza V, Noce G, Salamone EM, Del Percio C, Lopez S, Carducci F, Lizio R, De Bartolo M, Jakhar D, Afragola AP, Rossi C, Barjami L, Soricelli A, Salvatore M, Giubilei F, Güntekin B, Yener G, Massa F, Arnaldi D, Famà F, Pardini M, Ferri R, Lanuzza B, Stocchi F, Vacca L, Coletti C, Marizzoni M, Taylor JP,
Hanoğlu L, Yırıkoğulları H, Frisoni GB, Cuoco S, Cappiello A, Barone P, Bonanni L, D'Anselmo A, Biundo R, Cauzzo S, Fiorenzato E, Antonini A, D'Antonio F, Bruno G, Infarinato F, Marziali S, De Pandis MF, Babiloni C. Periodic and Aperiodic Electroencephalographic Rhythms During Vigilance Transitions in Alzheimer's Disease Mild Cognitive Impairment. Ann N Y Acad Sci. 2026 Jan;1555(1):e70194. doi: 10.1111/nyas.70194. PMID: 41589606.

2025

events and conference contributions

On 4th December 2025, an online meeting with the external legal and ethics advisors of the eBRAIN-Health project took place. In this context, CHARITE together with University of Vienna (UNIVIE) and Alzheimer Europe (AE) presented their work within the project and obtained feedback and guidance on the next steps within the project from the external experts. The legal and ethical advisors are accomplished figures from the fields of ethics, privacy and data protection law, and ICT technology.

Cyberspace Conference in Brno
Representing the eBRAIN-Health project, Klaudia Kwiatkowska and Alexandra Mǎrginean highlighted the legal status of synthetic data under the legal acts of the European Data Strategy, more specifically the Data Governance Act, Data Act and European Health Data Space. The presentation focused on the opportunities and challenges represented by synthetic data in medical research. In the context of the eBRAIN-Health project, synthetic data will be used to enrich machine learning and deep learning algorithms which will support early diagnosis of neurodegenerative diseases.

scientific publications

Lopez S, Del Percio C, Lizio R, Noce G, Jakhar D, Soricelli A, Salvatore M, Güntekin B, Yener G, Massa F, Arnaldi D, Famà F, Pardini M, Ferri R, Carducci F, Lanuzza B, Stocchi F, Vacca L, Coletti C, Marizzoni M, Taylor JP, Hanoğlu L, Yılmaz NH, Kıyı İ, Özbek-İşbitiren Y, D'Anselmo A, Bonanni L, Biundo R, D'Antonio F, Bruno G, Antonini A, Giubilei F, Cuoco S, Barone P, Frisoni GB, Rotondo R, De Pandis F, Babiloni C.
The compensatory effect of education as revealed by resting-state electroencephalographic alpha rhythms in patients with dementia due to Parkinson's disease: findings from an exploratory study. Geroscience. 2025 Jun 11. doi: 10.1007/s11357-025-01703-9. Epub ahead of print. PMID: 40498398

Lopez S, Hampel H, Percio CD, Noce G, Lizio R, Teipel SJ, Dyrba M, González-Escamilla G, Bakardjian H, Chiesa PA, Cavedo E, Vergallo A, Lemercier P, Spinelli G, Grothe MJ, Potier MC, Stocchi F, Coletti C, Ferri R, Pardini M, Habert MO, Marziali S, Dubois B, Babiloni C; and INSIGHT‐preAD study group.
Educational attainment, electroencephalographic rhythms, cortical structure, and cognitive performance over 2 years in older adults with subjective memory complaints and brain amyloidosis. Alzheimers Dement.
2025 Jul;21(7):e70438. doi: 10.1002/alz.70438. Erratum in: Alzheimers Dement. 2025 Aug;21(8):e70577. doi: 10.1002/alz.70577. PMID: 40660738; PMCID: PMC12260118

Enrico Michele Salamone, Matteo Carpi, Giuseppe Noce, Claudio Del Percio, Susanna Lopez, Roberta Lizio, Dharmendra Jakhar, Ali Eldellaa, Veronica Henao Isaza, Burcu Bölükbaş, Andrea Soricelli, Marco Salvatore, Bahar Güntekin, Görsev Yener, Federico Massa, Dario Arnaldi, Francesco Famà, Matteo Pardini, Raffaele Ferri, Michele Salerni, Bartolo Lanuzza, Fabrizio Stocchi, Laura Vacca, Chiara Coletti, Moira Marizzoni, John Paul Taylor, Lutfu Hanoğlu, Nesrin Helvacı Yılmaz, İlayda Kıyı, Hilal Kula, Giovanni B. Frisoni, Sofia Cuoco, Paolo Barone, Anita D’Anselmo, Laura Bonanni, Roberta Biundo, Fabrizia D’Antonio, Giuseppe Bruno, Franco Giubilei, Angelo Antonini, Claudio Babiloni
Abnormal electroencephalographic rhythms from quiet wakefulness to light sleep in Alzheimer’s disease patients with mild cognitive impairment - Clinical Neurophysiology

Del Percio C, Lizio R, Lopez S, Noce G, Carpi M, Jakhar D, Soricelli A, Salvatore M, Yener G, Güntekin B, Massa F, Arnaldi D, Famà F, Pardini M, Ferri R, Carducci F, Lanuzza B, Stocchi F, Vacca L, Coletti C, Marizzoni M, Taylor JP, Hanoğlu L, Yılmaz NH, K
Resting-State EEG Alpha Rhythms Are Related to CSF Tau Biomarkers in Prodromal Alzheimer’s Disease - IJMS

Claudio Del Percio, Roberta Lizio, Susanna Lopez, Giuseppe Noce, Dharmendra Jakhar, Matteo Carpi, Burcu Bölükbaş, Andrea Soricelli, Marco Salvatore, Bahar Güntekin, Görsev Yener, Federico Massa, Dario Arnaldi, Francesco Famà, Matteo Pardini, Raffaele Ferri, Michele Salerni, Bartolo Lanuzza, Fabrizio Stocchi, Laura Vacca, Chiara Coletti, Moira Marizzoni, John Paul Taylor, Lutfu Hanoğlu, Nesrin Helvacı Yılmaz, İlayda Kıyı, Yağmur Özbek-İşbitiren, Giovanni B. Frisoni, Sofia Cuoco, Paolo Barone, Anita D'Anselmo, Laura Bonanni, Roberta Biundo, Fabrizia D'Antonio, Giuseppe Bruno, Franco Giubilei, Francesca De Pandis, Rossella Rotondo, Angelo Antonini, Claudio Babiloni
Resting-state electroencephalographic rhythms depend on sex in patients with dementia due to Parkinson's and Lewy Body diseases: An exploratory study - Neurobiology of Disease

Babiloni C, Arakaki X, Baez S, Barry RJ, Benussi A, Blinowska K, Bonanni L, Borroni B, Bosch JB, Bruno G, Cacciotti A, Carducci F, Carino J, Carpi M, Conte A, Cruzat J, D’Antonio F, Della Penna S, Del Percio C, De Sanctis P, Escudero J, Fabbrini G, Farina
Alpha Rhythm and Alzheimer’s Disease: Has Hans Berger’s Dream Come True? - Clinical Neurophysiology

scientific reports

Open access pathway knowledge graphs
High throughput container workflows
Catalogue of multi-scale principles of brain dynamics in dementia
Patient and clinical user applications
Education app in multiple platforms
Identified biomarkers using explainable AI

2024

event and conference contributions

"The EBRAINS Project: A Gateway to Collaborative Neuroscience"
34th Alzheimer Europe Conference
27th annual meeting of the Association for the Scientific Study of Consciousness
BrainModes 2024
YRP2024
EOSC Symposium
ICCN2024
IPEG2024
CPDP.ai 2024
NeuroMI2024
NASA Human Research Program IWS
Spanish Society of Geriatrics and Gerontology

scientific publications

Berger M, Ryu D, Reese M, McGuigan S, Evered LA, Price CC, Scott DA, Westover MB, Eckenhoff R, Bonanni L, Sweeney A, Babiloni C
A Real-Time Neurophysiologic Stress Test for the Aging Brain: Novel Perioperative and ICU Applications of EEG in Older Surgical Patients Neurotherapeutics

Yoram Vodovotz; Yoram Vodovotz; Julia Arciero; Paul F. M. J. Verschure; David L. Katz; David L. Katz
A multiscale inflammatory map: linking individual stress to societal dysfunction Frontiers in Science

Ignacio Taguas; Sandra Doval; Fernando Maestú; David López-Sanz
Toward a more comprehensive understanding of network centrality disruption in amnestic mild cognitive impairment: a MEG multilayer approach - Alzheimer's Research & Therapy

Riccardo Leone; Steven Geysen; Gustavo Deco; Xenia Kobeleva
Beyond Focal Lesions: Dynamical Network Effects of White Matter Hyperintensities - Human Brain Mapping

Noelia Martínez-Molina; Yonatan Sanz-Perl; Anira Escrichs; Morten L. Kringelbach; Morten L. Kringelbach; Morten L. Kringelbach; Gustavo Deco; Gustavo Deco
Turbulent dynamics and whole-brain modeling: toward new clinical applications for traumatic brain injury - Frontiers in Neuroinformatics

Sami Hamdan, Shammi More, Leonard Sasse, Vera Komeyer, Kaustubh R. Patil, Federico Raimond
Julearn: an easy-to-use library for leakage-free evaluation and inspection of ML models - Gigabyte

Serio, Bianca; Hettwer, Meike D.; Wiersch, Lisa; Bignardi, Giacomo; Sacher, Julia; Weis, Susanne; Eickhoff, Simon B.; Valk, Sofie L.
Sex differences in functional cortical organization reflect differences in network topology rather than cortical morphometry - Nature Communications

Küchenhoff, Svenja; Bayrak, Şeyma; Zsido, Rachel G.; Saberi, Amin; Bernhardt, Boris C.; Weis, Susanne; Schaare, H. Lina; Sacher, Julia; Eickhoff, Simon; Valk, Sofie L.
Relating sex-bias in human cortical and hippocampal microstructure to sex hormones - Nature Communications

Michael Schirner, Gustavo Deco & Petra Ritter
Learning how network structure shapes decision-making for bio-inspired computing - Nature Communications

Dominik P. Koller; Michael Schirner; Petra Ritter
Human connectome topology directs cortical traveling waves and shapes frequency gradients - Nature Communications

Claudio Babiloni, Dharmendra Jakhar, Federico Tucci, Claudio Del Percio, Susanna Lopez, Andrea Soricelli, Marco Salvatore, Raffaele Ferri, Valentina Catania, Federico Massa, Dario Arnaldi, Francesco Famà, Bahar Güntekin, Görsev Yener, Fabrizio Stocchi, Laura Vacca, Moira Marizzoni, Franco Giubilei, Ebru Yıldırım, Lutfu Hanoğlu, Duygu Hünerli, Giovanni B. Frisoni, Giuseppe Noce
Resting state electroencephalographic alpha rhythms are sensitive to Alzheimer’s disease mild cognitive impairment progression at a 6-month follow-up - Neurobiology of Aging

Susanna Lopez, Harald Hampel, Patrizia Andrea Chiesa, Claudio Del Percio, Giuseppe Noce, Roberta Lizio, Stefan J. Teipel, Martin Dyrba, Gabriel González-Escamilla, Hovagim Bakardjian, Enrica Cavedo, Simone Lista, Andrea Vergallo, Pablo Lemercier, Giuseppe Spinelli, Michel J. Grothe, Marie-Claude Potier, Fabrizio Stocchi, Raffaele Ferri, Marie-Odile Habert, Bruno Dubois, Claudio Babiloni
The association between posterior resting-state EEG alpha rhythms and functional MRI connectivity in older adults with subjective memory complaint - Neurobiology of Aging

van der Vlag, Michiel; Kusch, Lionel; Destexhe, Alain; Jirsa, Viktor; Diaz, Sandra; Goldman, Jennifer S.
Vast Parameter Space Exploration of the Virtual Brain: A Modular Framework for Accelerating the Multi-Scale Simulation of Human Brain Dynamics - Applied Sciences

Daniela S. Avila-Varela; Esmeralda Hidalgo-Lopez; Paulina Clara Dagnino; Irene Acero-Pousa; Elvira del Agua; Gustavo Deco; Belinda Pletzer; Anira Escrichs
Whole-brain dynamics across the menstrual cycle: the role of hormonal fluctuations and age in healthy women - npj Women's Health

Anira Escrichs; Yonatan Sanz Perl; Patrick M. Fisher; Noelia Martínez-Molina; Elvira G-Guzman; Vibe G. Frokjaer; Morten L. Kringelbach; Gitte M. Knudsen; Gustavo Deco
Whole-brain turbulent dynamics predict responsiveness to pharmacological treatment in major depressive disorder - Molecular Psychiatry

Jesús Cabrera-Álvarez; Leon Stefanovski; Leon Martin; Gianluca Susi; Fernando Maestú; Petra Ritter
A Multiscale Closed-Loop Neurotoxicity Model of Alzheimer’s Disease Progression Explains Functional Connectivity Alterations - eneuro

Patrik Bey; Kiret Dhindsa; Amrit Kashyap; Michael Schirner; Jan Feldheim; Marlene Bönstrup; Robert Schulz; Bastian Cheng; Götz Thomalla; Christian Gerloff; Petra Ritter
A lesion‐aware automated processing framework for clinical stroke magnetic resonance imaging - Human Brain Mapping

Paulina Clara Dagnino; Anira Escrichs; Ane López-González; Olivia Gosseries; Jitka Annen; Yonatan Sanz Perl; Morten L. Kringelbach; Steven Laureys; Gustavo Deco
Re-awakening the brain: Forcing transitions in disorders of consciousness by external in silico perturbation - PLOS Computational Biology

Gustavo A. Patow; Anira Escrichs; Petra Ritter; Gustavo Deco
Whole-Brain Dynamics Disruptions in the Progression of Alzheimer's Disease: Understanding the Influence of Amyloid-Beta and Tau - bioRxiv

Kathrin Giehl, Henk-Jan Mutsaerts, Kristien Aarts, Frederik Barkhof, Svenja Caspers, Gaël Chetelat, Marie-Elisabeth Colin, Emrah Düzel, Giovanni B Frisoni, M Arfan Ikram, Jorge Jovicich, Silvia Morbelli, Wolfgang Oertel, Christian Paret, Daniela Perani, Petra Ritter, Bàrbara Segura, Laura E M Wisse, Elke De Witte, Stefano F Cappa, Thilo van Eimeren. (2024) Sharing brain imaging data in the Open Science era: how and why?. The Lancet Digital Health.

Katrin Amunts, Markus Axer, Swati Banerjee, [...], Petra Ritter, [...], Lisa Vincenz-Donnelly, Florian Walter, Laszlo Zaborszky. (2024) The coming decade of digital brain research: A vision for neuroscience at the intersection of technology and computing. Imaging Neuroscience

Russell A Poldrack, [...], Petra Ritter, [...], Michael Schirner, [...], Krzysztof J. Gorgolewski. (2024) The Past, Present, and Future of the Brain Imaging Data Structure (BIDS). eNeuro (in press)

scientific reports

Open access full metadata and ontology models
Open access data catalogue and variable mapping
Curated and harmonized data
Multiscale model visualizer
Demonstrator improving disease prediction
Demonstrator mechanism-based subclass identification
Quality control workflows implemented
Report on the AE conference symposium, and European Parliament lunch debate

2023

events, dissemination and communication

Nov. 29, XIV Annual Conference of the Health Cluster Portugal: "Health Business Portugal" – with Petra Ritter's talk: "The Charité Berlin Ecosystem and the TEF Health Project".
Oct. 23-26, SciDataCon 2023 – with Petra Ritter as panelist in session: "Standards for a FAIR Data Future: How to Advance Standardization in Data Management?".
Sep. 27, MCCHE Precision Convergence Webinar: "Moving towards Interpretable Models of Functioning Brains For Adaptive Real-World Behavior and Sustainable Health" – with Petra Ritter as panelist.
Sep. 14-15, 6th EU-Japan Workshop on Neurorobotics: "Healthcare and ageing in the era of AI" – with Petra Ritter's talk: "EU Reference Center: Testing and Experimentation Facility for Health AI and Robotics".
Mar. 28-31, HBP Summit 2023: "Achievements and future of digital brain research" – satellite event, exhibition day, talk and poster session.
The eBRAIN-Health Website is Now Live [Public Deliverable]

scientific publications

Michael Schirner, Gustavo Deco, Petra Ritter (2023). Learning how network structure shapes decision-making for bio-inspired computing. Nature Communications

Babiloni C, Noce G, Tucci F, Jakhar D, Ferri R, Panerai S, Catania V, Soricelli A, Salvatore M, Nobili F, Arnaldi D, Famà F, Buttinelli C, Giubilei F, Onofrj M, Stocchi F, Vacca L, Radicati F, Fuhr P, Gschwandtner U, Ransmayr G, Parnetti L, Marizzoni M, D'Antonio F, Bruno G, De Lena C, Güntekin B, Yıldırım E, Hanoğlu L, Yener G, Hünerli D, Taylor JP, Schumacher J, McKeith I, Frisoni GB, Antonini A, Ferreri F, Bonanni L, De Pandis MF, Del Percio C.
Poor reactivity of posterior electroencephalographic alpha rhythms during the eyes open condition in patients with dementia due to Parkinson's disease. Neurobiol Aging. 2024 Mar;135:1-14. doi: 10.1016/j.neurobiolaging.2023.11.010. Epub 2023 Nov 28. PMID: 38142464

Donaghy PC, Carrarini C, Ferreira D, Habich A, Aarsland D, Babiloni C, Bayram E, Kane JP, Lewis SJ, Pilotto A, Thomas AJ, Bonanni L; Alzheimer's Association International Society to Advance Alzheimer's Research and Treatment Lewy Body Dementias Prodromal Working Group.
Research diagnostic criteria for mild cognitive impairment with Lewy bodies: A systematic review and meta-analysis. Alzheimers Dement. 2023 Jul;19(7):3186-3202. doi: 10.1002/alz.13105. Epub 2023 Apr 24. PMID: 37096339; PMCID: PMC10695683.

scientific reports

Scoping review on digital twins for dementia research
Public catalogue of data sharing agreements
Dynamic principles of aging and neurodegeneration - simulation demonstrator

2022

events, dissemination and communication

Alzheimer Europe article: eBRAIN-Health project hosts online kick-off meeting
eBRAIN-Health Project Launch
EBRAINS press release: eBRAIN-Health project awarded funding by Horizon Europe
BIH press release: Millions in funding for brain simulation
eBRAIN-Health Project: Selected for EU Funding under the Horizon Program

scientific publication

Lista S, Vergallo A, Teipel SJ, Lemercier P, Giorgi FS, Gabelle A, Garaci F, Mercuri NB, Babiloni C, Gaire BP, Koronyo Y, Koronyo-Hamaoui M, Hampel H, Nisticò R; Neurodegeneration Precision Medicine Initiative (NPMI).
Determinants of approved acetylcholinesterase inhibitor response outcomes in Alzheimer's disease: relevance for precision medicine in neurodegenerative diseases. Ageing Res Rev. 2023 Feb;84:101819. doi: 10.1016/j.arr.2022.101819. Epub 2022 Dec 13. PMID: 36526257.