eBRAIN-Health

'The participation of the MIND Inria team in eBRAIN-Health has enabled the development of a new variable importance measure for predictive AI models. The scope of the project has incentivized the development of generic techniques that work with various data types, including images, tables, categorical, and continuous variables. The needs of the project have also incentivized new developments, such as the analysis of variable importance in causal treatment effect theory.'

Dr. Bertrand Thirion INRIA

'Being part of eBRAIN-Health has given Eodyne a unique opportunity to work directly with patients with Alzheimer’s disease and their relatives, allowing us to test our technologies in real-life contexts and better understand how they can be improved to meet their needs. This close interaction provides insights that are impossible to obtain in controlled lab settings and is essential for designing rehabilitation and cognitive support tools that truly make a difference for patients and caregivers. At the same time, the GDPR-compliant research infrastructure developed within eBRAIN-Health ensures that this work is grounded in robust, secure, and ethically managed data practices. This combination of real-world patient feedback and high-quality data governance is key to accelerating scientific progress and delivering impactful digital health solutions across Europe.'

Santiago Brandi Eodyne Systems SL

'The most valuable aspect of our participation in eBRAIN-Health is the possibility to work in an interdisciplinary environment with experts from fields such as neuroscience, computer science, and public involvement. The University of Vienna contributes to the project’s work by providing legal expertise and by supporting partners in ensuring the project’s legal compliance. This collaboration positively impacts the legal work conducted by us, as we are able to enrich our research with use cases from the project, as well as experiences from other disciplines.'

Prof. Dr. Nikolaus Forgó University of Vienna

'Our participation in eBRAIN-Health has been fundamental for advancing the clinical application of whole-brain computational models. The most valuable aspect has been the opportunity to test and share our tools through eBRAINS, facilitating broad scientific collaboration. Our organization actively contributes by developing dynamic models that reveal the underlying mechanisms of disorders such as Alzheimer's disease and disorders of consciousness. This work is crucial for predicting brain-state transitions and identifying new targets for stimulation, which we see as a transformative impact on European healthcare. Ultimately, these scientific advances may lay the foundation for personalised medicine, enabling clinicians to tailor interventions to a patient's unique brain dynamics.'

'Being part of eBRAIN-Health has been an exceptional opportunity to advance a truly integrated, European research infrastructure for sensitive health data. As a team of professional software engineers and research-technology specialists, we contribute by leading the technical development of the project’s central node platform, building on our long-standing experience with the Charité VRE and the HealthDataCloud. The close collaboration with the EBRAINS ecosystem, especially including the Knowledge Graph and openMINDS teams, has been highly valuable and resulted in a deeply interoperable, sustainable platform. We already see the emerging impact: researchers across and beyond the consortium can securely manage and discover sensitive datasets, helping accelerate neuroscience and health research across Europe.'

Dr. Stephane Pollentier Indoc Research Europe gGmbH

'Being part of eBRAIN-Health has been invaluable for advancing our work on BrainX3, a platform that integrates neuroimaging, electrophysiology, and whole-brain modelling into an accessible and interactive environment. Through this collaboration, we have been able to align BrainX3 with the needs of a broader scientific community, strengthening its role as a bridge between empirical data and computational brain models. What makes eBRAIN-Health particularly impactful is the consortium’s shared commitment to open and more accessible neuroscience tools. The consortium has accelerated our ability to deliver clinically relevant simulations and visualisation tools that can support personalised healthcare in Europe. We are excited to see how BrainX3 complements the wider eBRAIN-Health platform and helps researchers explore brain dynamics more intuitively.'

Prof. Dr. Paul Tiesinga Radboud University

'The most valuable aspect of our participation in eBRAIN-Health is the opportunity to strengthen our role as a key center within the European EBRAIN network for both primary and tertiary dementia prevention. Our organization contributes directly through the development and implementation of the SmartMe&You-TELEMAIA home telemonitoring platform, designed to assess cognitive functions and track major dementia risk factors. This collaboration is highly impactful as it integrates advanced scientific procedures, such as refining EEG signal ontology and ensuring Machine Learning result stability, into a unified, user-centric service. This integrated approach will advance healthcare in Europe by providing memory clinics and citizens with powerful tools for active aging, early diagnosis, and continuous remote monitoring of neurodegenerative conditions.'

Prof. Dr. Claudio Babiloni Sapienza University of Rome

'The eBRAIN-Health project has gathered academia from both technical and medical domains, patient associations, and private companies to work together towards the delivery of a distributed research platform. Adding more data references in the Knowledge Graph and the Health Data Cloud, and promoting the FAIR principles to annotate the data amongst more and more institutions, is one of our key takeaways from the participation in this project. We have shared our experience in data annotation and sharing, and we have understood the issues that are related to storing and sharing data from other institutions. We have helped one another build a stronger relationship amongst different research organisations. The variety of partners that are contributing to this project helped us further develop our knowledge and infrastructure by adding different perspectives to our vision.'